Antibiotic Resistant Bacteria (Deadly Diseases and - download pdf or read online

By Patrick Guilfoile

ISBN-10: 0791091880

ISBN-13: 9780791091883

ISBN-10: 1438101325

ISBN-13: 9781438101323

This carrying on with sequence explores various illnesses to teach the technological know-how at the back of how disease-causing organisms have an effect on the physique. Microorganisms have plagued people because the starting of time, inflicting debilitating illnesses or even demise. yet how, precisely, do those microorganisms infect and reason illness? The books during this sequence study numerous microbiological scourges that experience affected people in addition to the stairs which have been taken to spot, isolate, hinder, and remove them. every one identify will define the background and coverings of the ailments, highlighting how advancements in prevention and therapy strategies have affected the disease's impression at the global inhabitants.

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Extra info for Antibiotic Resistant Bacteria (Deadly Diseases and Epidemics)

Example text

A membrane protein in S. aureus, for example, is involved in pumping out ciprofloxacin and related drugs, along with chloramphenicol. 7). Recall that sulfonamides mimic PABA, so an overabundance of this chemical means the antibiotics will have difficulty reaching their target. So much PABA will be available that the enzyme will likely always have PABA in its active site, the same location targeted by the antibiotic. Trimethoprim resistance often results from overproduction of the enzyme (called dihydrofolate reductase, DHFR) targeted by the antibiotic.

Added to the problem of rapid bacterial multiplication is the selective pressure exerted by the huge volume of antibiotics used in human medicine and agriculture. C04_P4 60 3/6/08 8:46 AM Page 60 ANTIBIOTIC-RESISTANT BACTERIA antibiotic usage is inappropriate and is increasingly leading to disease transmission in animals and humans, as highlighted in the opening story of this chapter. Recent data indicates the extent of the growing antibioticresistance problem. In Escherichia coli, for example, 80 percent of strains in some countries are resistant to ampicillin, which has been used to treat E.

Following the surgery, he developed diarrhea, caused by a microbe called Salmonella enterica. This particular strain was resistant to a wide range of antibiotics including ampicillin, aztreonam, cefoxitin, ceftriaxone, cephalothin, chloramphenicol, gentamicin, kanamycin, sulfamethsoxizole, streptomycin, tetracycline, and tobramycin. Fortunately, the boy’s immune system was able to fight the infection, and he recovered. Further investigation revealed that cattle on his ranch and neighboring ranches were treated for Salmonella infections a month before he became infected.

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Antibiotic Resistant Bacteria (Deadly Diseases and Epidemics) by Patrick Guilfoile


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